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目的探讨经导管局部溶栓治疗下肢深静脉血栓形成(DVT)的溶栓时间与疗效关系。方法56例患者,病程1~14 d者22例(A组),病程15~40 d者34例(B组)。全部患者均经右颈内静脉途径置入导管行尿激酶溶栓治疗。结果A组:导管溶栓时间为5~11 d,平均为(7.1±5.9)d;血栓完全溶解19例(86.4%),部分溶解3例(13.6%)。B组:导管溶栓时间为7~18 d,平均为(11.3±7.2)d,显著高于A组(P<0.05),血栓完全溶解28例(82.4%),部分溶解6例(17.6%),2组比较差异无统计学意义(P>0.05)。结论对于病程较长的下肢DVT,延长导管溶栓时间,可获得较好的疗效。
Objective To investigate the relationship between thrombolysis time and curative effect of transcatheter partial thrombolysis for deep vein thrombosis (DVT). Methods Totally 56 patients were included in this study. Twenty - two patients (group A) with duration of 1 to 14 days and 34 patients (group B) with duration of 15 to 40 days. All patients were catheterized by urokinase thrombolysis through the right internal jugular vein. Results In group A, the duration of catheter thrombolysis was 5 to 11 days (mean, 7.1 ± 5.9) days. Thrombus was completely dissolved in 19 (86.4%) and partially dissolved in 3 (13.6%). In group B, the thrombolysis time was 7 to 18 days (mean, 11.3 ± 7.2 days), significantly higher than that in group A (28.4%), partially dissolved in 6 cases (17.6% ), No significant difference between the two groups (P> 0.05). Conclusion DVT with longer course of lower extremity can prolong the time of catheter thrombolysis and obtain better curative effect.