论文部分内容阅读
目的 评估妊娠滋养细胞肿瘤膀胱转移患者的治疗方法及临床预后。方法 回顾性分析 1988～ 1999年收治的滋养细胞肿瘤 (GTT)膀胱转移患者共 10例。所有患者均接受以 5 -氟尿嘧啶 (5 -FU)为主的联合化疗或EMA/ CO化疗 ,同时行 5 -FU膀胱灌注 ,部分患者行选择性动脉插管栓塞术。结果 10例患者中 ,2例合并脑转移死亡 ,1例血生化指标缓解带瘤存活 ,7例治愈。结论 滋养细胞肿瘤膀胱转移患者经过正规的全身加局部化疗 ,疗效较好。选择性动脉插管栓塞可以作为急诊处理膀胱转移大出血患者的首选方法
Objective To evaluate the treatment and clinical prognosis of gestational trophoblastic tumor with bladder metastasis. Methods A total of 10 patients with bladder metastasis of gestational trophoblastic (GTT) from 1988 to 1999 were retrospectively analyzed. All patients received 5-fluorouracil (5-FU) -based combination chemotherapy or EMA / CO chemotherapy while 5-FU intravesical instillation. In some patients, selective arterial embolization was performed. Results Of the 10 patients, 2 patients died of brain metastasis, 1 blood biochemical index relieved the tumor survival and 7 patients were cured. Conclusion Trophoblastic tumor patients with bladder metastasis after formal systemic plus local chemotherapy, better effect. Selective arterial embolization can be the first choice for emergency treatment of patients with massive bladder metastasis