论文部分内容阅读
目的 观察两种不同材料制备的膜型血浆分离器Evacure-4A与PS-06进行血浆置换治疗重型肝炎的疗效。方法 63例患者在内科综合治疗基础上联合血浆置换治疗,其中应用Evacure-4A膜型血浆分离器28例(A组),应用PS-06膜型血浆分离器35例(B组),检测治疗前、后肝功能。结果 经单次血浆置换治疗后,两组患者的总胆红素及直接胆红素明显降低,A组患者分别下降(41.6±10.6)％和(42.1±11.9)％,B组患者分别下降(42.1±11.9)％和(43.4±8.3)％,两组比较t值分别为0.98和0.7 3,P值均>0.05;两组患者血清白蛋白水平均有轻度升高,A组血清白蛋白上升幅度大于B组,A组为(8.3±10.7)％,B组为(3.4±9.3)％,t=2.76,P<0.01。结论 膜型血浆分离器Evacurc-4A可以减少白蛋白丢失,优于膜型血浆分离器PS-06。
Objective To observe the curative effect of plasma exchange of Evacure-4A and PS-06 on two kinds of membranous plasma separators for the treatment of severe hepatitis. Methods Sixty-three patients were treated with Evacure-4A membranous plasma separator (group A) and 35 patients with PS-06 membranous plasma separator (group B) Before and after liver function. Results After a single plasma exchange, total bilirubin and direct bilirubin were significantly decreased in both groups, with a decrease of (41.6 ± 10.6)% and (42.1 ± 11.9)% in group A and a decrease in group B ( 42.1 ± 11.9)% and (43.4 ± 8.3)%, respectively. The t values of the two groups were 0.98 and 0.7 3, respectively, with P values> 0.05. Serum albumin levels were slightly elevated in both groups. Serum albumin (8.3 ± 10.7)% in group A, (3.4 ± 9.3)% in group B, t = 2.76, P <0.01. Conclusion Membrane plasma separator Evacurc-4A can reduce the albumin loss, superior to the membrane type plasma separator PS-06.