中药889对人白血病粒细胞、肝癌和绿猴肾细胞生长的影响

来源 :中国中医基础医学杂志 | 被引量 : 0次 | 上传用户:jinshu
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目的:为了探讨中药889对体外培养的癌细胞的影响。方法:我们观察了该药对人白血病粒细胞(K562)、肝癌细胞(Heper)和绿猴肾细胞(Versens,为正常细胞)生长的影响。结果:浓度在20.83~41.67μg/ml、作用时间为24~48h时,K562细胞死亡率和抑制率分别为80.67~68.33%和86.27~70.10%;Heper细胞抑制率为60.98~75.94%,与空白对照组相比,P<0.05和0.01,而对Versens细胞生长无影响。结论:我们初步认为该药有较强的抑制癌细胞生长和繁殖的能力 Objective: To investigate the effect of Chinese medicine 889 on cancer cells cultured in vitro. METHODS: We observed the effect of the drug on the growth of human leukemic granulocytes (K562), hepatoma cells (Heper) and green monkey kidney cells (Versens, normal cells). Results: At the concentration of 20.83~41.67μg/ml and the action time of 24~48h, the mortality and inhibition rate of K562 cells were 80.67~68.33% and 86.27~70.10% respectively; The cell inhibition rate was 60.98-7.94%. Compared with the blank control group, P<0.05 and 0.01, but had no effect on Versens cell growth. Conclusion: We initially believe that this drug has a strong ability to inhibit the growth and reproduction of cancer cells.
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