突触传递的长时程增强 (LTP)是学习记忆的神经基础之一 ,是突触可塑性的功能性指标之一 ,也是研究学习记忆的理想模型。LTP是突触前后机制共同作用的结果 ,包括诱导和维持 2个阶段。LTP的形成与突触前递质的释放、突触后相关受体通道以及各种蛋白激酶、逆行信使、即早基因等密切相关。 Synaptic transmission of long-term potentiation (LTP) is one of the neural basis for learning and memory, is one of the functional indicators of synaptic plasticity, but also an ideal model for studying learning and memory. LTP is the result of a combination of presynaptic mechanisms, including induction and maintenance of two phases. The formation of LTP is closely related to the release of presynaptic neurotransmitters, postsynaptic receptor channels and various protein kinases, retrograde messengers, ie early genes.