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目的探讨脂蛋白(α)结合胆红素检验在冠心病(CHD)临床诊断中的可行性。方法 40例冠心病患者作为观察组,并取同期健康体检者40例作为参照组。两组研究对象均采用生化分析,比较两组研究对象的脂蛋白(α)、间接胆红素、直接胆红素以及总胆红素水平。结果观察组的总胆红素、间接胆红素、直接胆红素以及脂蛋白(α)水平分别为(8.15±2.06)μmol/L、(5.64±2.72)μmol/L、(2.74±1.16)μmol/L、(304.14±102.25)mg/L;参照组分别为(14.21±3.16)μmol/L、(6.82±3.45)μmol/L、(3.17±1.33)μmol/L、(165.01±72.12)mg/L。观察组总胆红素水平显著低于参照组,脂蛋白(α)浓度显著高于参照组,差异均具有统计学意义(P<0.05);两组的间接胆红素、直接胆红素水平比较差异无统计学意义(P>0.05)。结论脂蛋白(α)、总胆红素和冠心病有关系,故检测两项指标可提高冠心病诊断的准确率。
Objective To investigate the feasibility of lipoprotein (α) conjugated bilirubin test in the clinical diagnosis of coronary heart disease (CHD). Methods 40 patients with coronary heart disease as observation group, and take the same period of health examination in 40 cases as a reference group. Both groups were biochemically analyzed to compare the levels of lipoprotein (α), indirect bilirubin, direct bilirubin, and total bilirubin in both study groups. Results The levels of total bilirubin, indirect bilirubin, direct bilirubin and lipoprotein in the observation group were (8.15 ± 2.06) μmol / L, (5.64 ± 2.72) μmol / L and (2.74 ± 1.16) (14.21 ± 3.16) μmol / L, (6.82 ± 3.45) μmol / L, (3.17 ± 1.33) μmol / L, (165.01 ± 72.12) mg / / L. The level of total bilirubin in the observation group was significantly lower than that of the reference group, and the concentration of lipoprotein (α) was significantly higher than that of the reference group (P <0.05). The levels of indirect bilirubin and direct bilirubin The difference was not statistically significant (P> 0.05). Conclusion There is a relationship between lipoprotein (α), total bilirubin and coronary heart disease. Therefore, the detection of two indexes can improve the diagnostic accuracy of coronary heart disease.