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目的探讨沙美特罗联合噻托溴铵治疗老年支气管哮喘患者的临床效果。方法选取2012年12月至2015年1月吉林省人民医院收治的288例老年支气管哮喘患者作为研究对象,按随机数字表法将其分为对照组和观察组,各144例。对照组患者在常规治疗基础上给予沙美特罗气雾剂,观察组患者在对照组基础上采用噻托溴铵粉雾剂进行治疗,比较两组患者的治疗效果及不良反应发生情况。结果观察组患者治疗的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患者的不良反应发生率明显低于对照组,差异有统计学意义(χ2=6.868,P<0.05)。结论沙美特罗联合噻托溴铵治疗老年支气管哮喘患者临床效果明显,不良反应少,可明显提高患者的生命质量。
Objective To investigate the clinical efficacy of salmeterol combined with tiotropium in elderly patients with bronchial asthma. METHODS: A total of 288 elderly patients with bronchial asthma admitted from Jilin Provincial People’s Hospital from December 2012 to January 2015 were selected as study subjects and divided into control group and observation group according to random number table method, with 144 cases in each group. Patients in the control group were given salmeterol aerosol on the basis of routine treatment. Patients in the observation group were treated with tiotropium bromide aerosol on the basis of the control group. The treatment effect and adverse reactions of the two groups were compared. Results The total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P <0.05). The incidence of adverse reactions in observation group was significantly lower than that of control group (χ2 = 6.868, P <0.05). Conclusion Salmeterol combined tiotropium treatment of elderly patients with bronchial asthma clinical effect is obvious, fewer adverse reactions, can significantly improve the quality of life of patients.