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作者等报告1例免疫缺陷病人于外生殖器和口腔发生乳头瘤病毒16型(HPV-16)感染,并与舌部鳞状细胞癌有关.本例提示HPV-16在口腔癌的致病原因中起重要的作用.患者男性,33岁,舌右侧肿胀6个月,以往因SLE用强的松治疗14年.后又因隐球菌性脑膜炎经用二性霉素B及5-FC治愈.住院后发现左臂有多发性扁平疣.1981年阴茎及阴囊发生疣状皮疹.1984年发现该部位的丘疹融
The authors reported that 1 patient with immunodeficiency developed HPV-16 infection in the external genitalia and oral cavity and was associated with lingual squamous cell carcinoma. This case suggests that HPV-16 is a cause of oral cancer. It plays an important role. The patient is male, 33 years old, and the right side of the tongue is swollen for 6 months. In the past, SLE was treated with prednisone for 14 years. Afterwards, cryptococcal meningitis was treated with amphotericin B and 5-FC. After hospitalization, multiple flat warts were found in the left arm. In the 1981, a pustular rash occurred in the penis and scrotum. In 1984, the pimples were found in the area.