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目的 :探讨红景天与乙酰唑胺对进驻高原青年睡眠剥夺及亚极量运动心率的影响 ;方法 :将进驻海拔 3 70 0m一个月的 2 4名健康青年随机分为 3组 ,每组 8人 ,让受试者用EGM型踏车功量机做坐位踏车运动 ,初始负荷功率 2 5W ,每 3min递增 2 5W ,直至力竭 ,用直线回归法计算每位受试者负荷功率 90W时运动心率 (HR90W) ,第二次实验为 2 4h睡眠剥夺后 ;第三次实验为 3组受试者分别口服三普红景天、乙酰唑胺和安慰剂 2 0d后 ;第四次实验为服药后 2 4h睡眠剥夺后 ,实验方法与第一次相同 ;结果 :红景天组和乙酰唑胺组服药后与服药后睡眠剥夺后HR90W 较服药前、睡眠剥夺后及对照组明显降低 ,差异非常显著(P <0 .0 1 ) ,但乙酰唑胺对人体有不良反应 ;结论 :三普红景天与乙酰唑胺均能改善高原移居青年的肺通气及提高做功效率 ,三普红景天优于乙酰唑胺。
Objective: To investigate the effects of rhodiola rosea and acetazolamide on sleep deprivation and sub-maximal exercise-induced heart rate in high altitude places. Methods: Forty-four healthy youths at an altitude of 3 70 m were divided into three groups randomly People, so that subjects with EGM-type treadmill power machine seat rotation exercise, the initial load power of 25W, an increase of 2 5W every 3min, until exhaustion, using linear regression method to calculate the load power of each subject 90W Exercise heart rate (HR90W), the second experiment was 24 h after sleep deprivation; the third experiment for the three groups of subjects were oral Rhodiola, acetazolamide and placebo 20d; the fourth experiment After 24 h sleep deprivation, the experimental method was the same as that of the first time. Results: HR90W of Rhodiola group and acetazolamide group was significantly lower than that before medication and after sleep deprivation and the control group (P <0.01), but acetazolamide had adverse reactions to the human body.CONCLUSIONS: Rhodiola saponin and acetazolamide can both improve lung ventilation and improve work efficiency in high altitude migrant youth. Day is better than acetazolamide.