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Human erythrocyte complement receptor type 1 (CR1),also known as CD35,is a large single-chain transmembrane glycoprotein and an immune adherence receptor of complement component 3b/4b [1].Its amino acid composition and genetic structure have been reported [2].In primate,when the erythrocytes bounded with immune complexes (ICs)moved through the liver and spleen,only the ICs were removed by sinusoidal macrophages and the erythrocytes were allowed to retu to the circulation [3].CR1 has received many studies in many species in recent yearsdue to its important role in mammalian immune system activation [4,5].However,up to date,porcine CR1-like protein is rarely reported.