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目的:观察二氧化碳激光去除疣体后再外用匹多莫德的疗效。方法:在应用二氧化碳激光去除疣体的基础上再外用匹多莫德治疗尖锐湿疣64例,其中男43例,女21例,并与62例使用重组干扰素a-2b的对照组患者比较。结果:治疗组64例患者中,痊愈53例(占82.8%),复发11例(仅占17.2%);对照组62例中,痊愈38例(占61.3%),复发24例(占38.7%)。两组复发率比较,差异有统计学意义(x~2=7.52,P<0.01)。结论:在二氧化碳激光去除疣体后应用匹多莫德可使患者伤口愈合时间明显缩短,有效地减少抗生素的应用,并能明显降低尖锐湿疣的复发率。
Objective: To observe the curative effect of pidotimod after external application of carbon dioxide laser to remove wart. Methods: Sixty-four cases of condyloma acuminatum were treated with pidotimod on the basis of carbon dioxide laser to remove the warts, including 43 males and 21 females, which were compared with 62 control patients who received recombinant interferon a-2b. Results: In the 64 cases of treatment group, 53 cases were cured (82.8%) and 11 cases (17.2%) were cured; in the control group, 38 cases (61.3%) were cured and 24 cases (38.7% ). The recurrence rate of the two groups, the difference was statistically significant (x ~ 2 = 7.52, P <0.01). Conclusion: The application of pidotimod after removing the wart by carbon dioxide laser significantly shortened the wound healing time, effectively reduced the application of antibiotics and significantly reduced the recurrence rate of condyloma acuminatum.