论文部分内容阅读
用以氨基甲酸乙酯麻醉的大鼠分析了雨蛙肽对体内和离体胃运动的不同效应。静脉注射雨蛙肽(60ng/kg)引起胃内压的下降和迷走神经胃支离中活动的同步减少。但是,全部切断迷走神经胃支后雨蛙肽对胃运动的效应抑制消失或反转为兴奋效应。雨蛙肽对离体胃肌条片的运动则有刺激作用。这种效应被阿托品所消除。根据以上结果认为,雨蛙肽对整体内的胃运动有抑制和兴奋二种效应。前者主要通过迷走神经,而后者则直接刺激胆硷能壁内神经元而实现的。在整体内,两蛙肽对胃运动的抑制作用占优势,其兴奋性影响不易显现。
Rats anesthetized with urethane were analyzed for different effects of the phytomer on gastric motility in vitro and in vivo. Intravenous injection of melatonin (60 ng / kg) caused a decrease in gastric pressure and a simultaneous decrease in activity in gastric vagus nerve. However, all the cut off the vagus nerve branch of the rain frog peptide on gastric motility inhibition disappeared or reversed for the excitement effect. Hyriomovirus peptide muscle strips on the excitement of exercise. This effect is eliminated by atropine. Based on the above results, it is concluded that the phytolalcytisine exerts both inhibitory and excitatory effects on the overall gastric motility. The former mainly through the vagus nerve, while the latter directly stimulate the cholinergic intramural neurons and achieved. In the whole, two frog peptides on gastric motility inhibition predominance, its excitability is not easy to show.