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2004年美国糖尿病学会(ADA)年会Banting奖获得者Michael Brownlee博士发表了统一机制学说,即无论糖尿病大血管(心脑血管及下肢血管)还是微血管(如肾、神经和视网膜)并发症都有一个共同的发病机制——氧化应激,而同年欧洲糖尿病研究学会(EASD)年会最高奖获得者Ceriello教授发表共同土壤学说,仍认为氧化应激是胰岛素抵抗、糖尿病和心血管疾病的共同发病基础。近年来关于
Dr. Michael Brownlee, recipient of the 2004 Banting Prize at the American Diabetes Society (ADA), published a Unified Mechanisms doctrine that both diabetic and cardiovascular (cardiovascular, and lower extremity vessels) or microvascular (renal, neurological and retinal) complications have A common pathogenesis - oxidative stress, while Professor Ceriello, the winner of the annual meeting of the European Association for Diabetes Research (EASD), in the same year, published a common soil doctrine that oxidative stress is still thought to be a co-morbidity of insulin resistance, diabetes and cardiovascular disease basis. In recent years about