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目的 观察应用尼卡地平治疗心肺转流期间高血压的临床效果.方法 选择20例在心肺转流中出现高血压的心脏手术惠者,单次静注尼卡地平0.04mg/kg降压,观察患者用药前后平均动脉压(MAP)的变化.结果 全组血压均出现明显下降,降压前MAP平均(83.7±5.6)mmHg,静注尼卡地平1min后MAP下降至(55.2±8.2)mmHg(P<0.01),至用药后20min,MAP始终维持低于降压前水平(P<0.05).结论 尼卡地平能有效治疗心脏手术心肺转流期高血压,减少并发症.“,”Objective To approach the clinic effect of nicardipine on treating hypertension during extracorporeal circulation (ECC). Methods 20 patients undergoing heart operation , who appeared hypertension during ECC, were given nieardipine 0. 04 mg/kg into oxygenator for a single - dose. Mean arterial blood pressure (MAP) were recorded during ECC. Results The BP of all the groups fell significantly. MAP fell to (55.2±8.2) mmHg (P<0.01) after injection of nicardipine abruptly from (83.7±5. 6)mmHg before operation, the effect persisted for 20 min (P<0.05). Conclusion Nicardipine can prevent from hypertension effectively during ECC in heart operation and reduce complications.