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目的探讨LEEP刀宫颈环形电切术治疗宫颈上皮内瘤变(CIN)的临床疗效、并发症等。方法通过对2006年1月-2008年12月行阴道镜下活检病理诊断为CIN的256例患者行LEEP刀宫颈环形电切术者随访并行回顾分析。结果阴道镜下活检病理诊断与最后诊断的符合率为88.67%(227/256),252例患者术后1年细胞学检查均转阴性(100%),其中245例人乳头状瘤病毒(HPV)DNA阳性患者中,238例术后1年HPVD-NA转为阴性(97.14%)。结论 LEEP刀宫颈环形电切术具有手术操作简单、并发症少、疗效高等特点,是一种理想的CIN诊治方法。
Objective To investigate the clinical efficacy and complications of cervical epithelial neoplasia (CIN) treated with LEEP knife electrosurgical ring electrotomy. Methods We retrospectively analyzed the follow-up of 256 patients who underwent colposcopic biopsy pathological diagnosis of CIN from January 2006 to December 2008. Results The coincidence rate of pathological diagnosis and final diagnosis of colposcopic biopsy was 88.67% (227/256). 252 cases were negative (100%) after one year cytology, including 245 cases of human papilloma virus (HPV). Among the DNA positive patients, 238 cases had a negative HPVD-NA at 1 year (97.14%). Conclusion The LEEP knife cervical loop electrosurgical technique has the advantages of simple operation, few complications and high curative effect. It is an ideal method for diagnosis and treatment of CIN.