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目的探讨尿螨病的实验诊断方法。方法对69例尿螨病患者进行尿螨分离、血常规检查、皮肤挑刺试验、血清总IgE、螨特异性IgE的检测。结果69例尿螨病患者的尿液中共分离出17种病原螨,其中粉螨14种。白细胞计数在(5.3～11.4)×109/L之间,白细胞分类一般为0.05～0.09之间,最高达0.48;嗜酸性粒细胞计数多在(0.5～0.14)×10~9/L之间。皮肤挑刺试验均呈阳性,“+++”、“++”和“+”者分别占52.17%(36/69)、39.13%(27/69)和8.70%(6/69)。尿螨阳性者和阴性者血清总IgE、螨特异性IgE分别为(89±22)IU/ml、(71±22)IU/ml和(35±27)IU/ml、(29±18)IU/ml,差异具显著性(P<0.01-P<0.05)。结论实验室诊断尿螨痛以尿螨分离为金标准,皮肤挑刺试验、血清总IgE和粉螨特异性IgE的检测可作为辅助诊断指标。
Objective To explore the experimental diagnosis of urinary mite disease. Methods 69 cases of urinary mite patients were tested for urine mites, blood tests, skin prick tests, total serum IgE and mite specific IgE. Results A total of 17 kinds of pathogenic mites were isolated from the urine of 69 cases of urolithiasis, including 14 kinds of acaroid mites. The white blood cell count was between (5.3 ~ 11.4) × 109 / L, the classification of white blood cells was between 0.05 ~ 0.09 and the highest was 0.48. The number of eosinophils was between (0.5 ~ 0.14) × 10 ~ 9 / L. The prick tests on the skin were all positive, with “+++”, “++” and “+” accounting for 52.17% (36/69), 39.13% (27/69) and 8.70% (6 / 69). The total serum IgE and mite-specific IgE of the positive and negative mite were 89 ± 22 IU / ml, 71 ± 22 IU / ml, 35 ± 27 IU / ml, 29 ± 18 IU / / ml, the difference was significant (P <0.01-P <0.05). Conclusion The laboratory diagnosis of urinary mite pain is the gold standard for the separation of urine mites. The tests of skin prick test, serum total IgE and acaroid mite-specific IgE can be used as auxiliary diagnostic indicators.