家兔巨噬细胞所产生的一种单因子具有抑制成纤维细胞增殖的作用。此单因子的制备如下,用石蜡油注射到新西兰家兔的腹腔内,诱发非特异性的免疫反应。7天后冲洗腹腔收集炎性细胞,接种在含5％胎牛血清的McCoy 5A A single factor produced by rabbit macrophages has the effect of inhibiting the proliferation of fibroblasts. The single factor was prepared by injecting paraffin oil into the abdominal cavity of New Zealand rabbits to induce a nonspecific immune response. After 7 days, the peritoneal cavity was collected and inflammatory cells were seeded in McCoy 5A with 5% fetal bovine serum