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1.多烯抗生素类制霉菌素局部用药治疗皮肤粘膜念珠菌感染疗效优于克霉唑,每日2～3次,1～2周或直至病损痊愈。两性霉素B 局部用药治疗皮肤和粘膜念珠菌感染有效。静脉注射治疗全身真菌感染。对隐球菌病和播散性念珠菌病,联用5-氟胞嘧啶有相加作用并可减少耐药菌株形成。两性霉素B不易进入脑脊液,中枢神经系统真菌感染者应鞘内给药。本品静脉注射应缓慢。试验量两性霉素B1mg加入5%葡萄糖200 ml内,2小时滴入。。一般开始量每日0.25 mg/kg,据病人
1 polyene antibiotics nystatin topical treatment of skin mucosal candidal infection better than clotrimazole, 2 to 3 times a day, 1 to 2 weeks or until the lesion healed. Amphotericin B topical treatment of skin and mucosal Candida infections effective. Intravenous injection for the treatment of systemic fungal infections. Cryptococcosis and disseminated candidiasis, combined with 5-fluorocytosine add and can reduce the formation of drug-resistant strains. Amphotericin B is not easy to enter the cerebrospinal fluid, central nervous system fungal infections should be administered intrathecally. This product intravenous injection should be slow. Test amount of amphotericin B1mg added 5% glucose 200 ml, 2 hours instillation. . The general starting amount of 0.25 mg / kg daily, according to the patient