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目的:观察益气活血化浊方对IV期糖尿病肾病的临床疗效。方法:将80例IV期糖尿病肾病患者随机分为治疗组和对照组各40例。方法:治疗组采用常规加益气活血化浊方口服治疗,对照组采用常规治疗,2个月为1疗程,结束后比较空腹及餐后2小时血糖、糖化血红蛋白、胆固醇、甘油三酯、24h尿蛋白定量(24h UP)、血肌酐(SCr)、尿素氮(BUN)。结果:治疗组空腹及餐后2小时血糖、糖化血红蛋白、胆固醇、甘油三酯、24h尿蛋白定量(24h UP)、血肌酐(SCr)、尿素氮(BUN)的改善均优于对照组(P<0.05)。结论:益气活血化浊方治疗糖尿病肾病具有较好的临床疗效,值得进一步推广。
Objective: To observe the clinical effect of Yiqi Huoxue Huazhuo prescription on stage IV diabetic nephropathy. Methods: 80 patients with stage IV diabetic nephropathy were randomly divided into treatment group and control group, 40 cases each. Methods: The treatment group was treated with conventional Yiqi Huoxue Huazhuo decoction. The control group was treated with conventional therapy for two months for one course of treatment. After fasting and 2 hours postprandial blood glucose, glycosylated hemoglobin, cholesterol, triglyceride, 24h Urine protein (24h UP), serum creatinine (SCr), blood urea nitrogen (BUN). Results: The improvement of fasting and postprandial blood glucose, glycosylated hemoglobin, cholesterol, triglyceride, 24 h urinary protein (24h UP), serum creatinine (SCr) and blood urea nitrogen (BUN) <0.05). Conclusion: Yiqi Huoxue Huazhuo prescription for the treatment of diabetic nephropathy has a good clinical efficacy, it is worth further promotion.