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作者对因急性胃肠道出血作急诊内镜检查而发现之132名活动性出血性溃疡患者随机分两组进行双盲治疗试验。一组(68例)在溃疡出血处或其周围多点(每点0.5毫升)经内镜注射1:10,000去甲肾上腺素,直至所有出血处均止血,平均用量9.6毫升;另一组(64例)则经大通道之治疗内镜作热探头治疗,探头直接置于出血点,并紧贴压迫之。每处予以3～4脉冲(每脉冲25～30焦耳),每次治疗平均9.5脉冲。治疗后,所有患者都静脉接受H_2-受体阻断剂。24小时后常规复作内镜检查,若再现活动性出血,则用同一方法再治疗之。如符合下列条件之一,则予急诊手术:1.输血4 U后血压及脉搏仍不稳定;2.总输血量超过8 U;3.出现呕血,或鼻胃管中抽出红色物示再出血,并伴心动过速及/或低血压。
The authors of acute gastrointestinal bleeding for emergency endoscopy and found that 132 patients with active hemorrhagic ulcer were randomly divided into two groups for double-blind treatment. One group (n = 68) received endoscopic injection of 1: 10,000 norepinephrine at or around ulcer bleeding (0.5 ml each) until all hemorrhages were hemostatic with an average of 9.6 ml; the other group (64 For example) is treated by the treatment of endoscopic heat treatment probe, the probe directly placed in the bleeding point, and close to oppression. Each to be 3 to 4 pulses (25 to 30 joules per pulse), each treatment average of 9.5 pulses. After treatment, all patients received intravenous H 2 -receptor blockers. After 24 hours routine compound endoscopy, if the recurrence of active bleeding, then use the same method of re-treatment. If one of the following conditions are met, emergency surgery is performed: 1. The blood pressure and pulse are still unstable after transfusion of 4 U; 2. Total blood transfusion exceeds 8 U; 3. Hematemesis occurs or red blood is drawn out from the nasogastric tube With tachycardia and / or hypotension.