1997年3月15日武平县城关卫生院预防接种门诊对4名7岁儿童按常规三角肌肌肉注射白破二联疫苗0.5ml,当天晚上,4名儿童出现轻度发热,注射部位搔痒、红肿伴微痛等症状,次日加重。查体:4名患儿均有轻度发热,体温在37.5～38.5C之间,注射部位均有红肿、皮肤发亮,其中3例红肿波及至肘关节,1例红肿波及至腕关节。一般情况良好。根据临床症状及疫苗接种史,认为是由接种白破二联疫苗引起的血管神经性水肿。4例均给予抗过敏治疗,并在注射部位热敷处理,3天后4例患儿肿胀消 March 15, 1997 Wuping County Chengguan Hospital outpatient vaccination of four 7-year-old children according to the conventional deltoid muscle injection of white diphtheria vaccine 0.5ml, same day night, 4 children with mild fever, injection site itching, redness With slight pain and other symptoms, the next day increased. Examination: 4 children with mild fever, body temperature between 37.5 ~ 38.5C, the injection site are inflamed, shiny skin, including 3 cases of swelling to the elbow, a case of swelling and swelling to the wrist. Generally good. According to the clinical symptoms and vaccination history, that is caused by inoculation of white broken vaccines induced neurovascular edema. 4 cases were given anti-allergy treatment, and heat treatment at the injection site, 3 days after 4 cases of children with swelling