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目的:观察糖尿病患者血清白细胞介素6(IL- 6) 的水平变化。方法:应用放射免疫分析法检测50 例糖尿病患者血清IL- 6 水平,并将患者分为无并发症组(A 组) 、急性并发症组(B 组) 及慢性并发症组(C组) 。结果:糖尿病患者IL- 6 水平显著高于正常( P< 0 .05) ,且糖尿病急、慢性并发症组IL- 6 水平增高更明显( P< 0 .01) 。结论:IL- 6 可能参与糖尿病的病理变化过程,并可作为临床上判断病情的指标。
Objective: To observe the level of serum interleukin 6 (IL-6) in diabetic patients. Methods: Serum IL-6 levels were measured by radioimmunoassay in 50 diabetic patients. Patients were divided into non-complication group (A group), acute complication group (B group) and chronic complication group (C group). Results: The levels of IL-6 in diabetic patients were significantly higher than those in normal controls (P <0.05). The levels of IL-6 in diabetic patients with acute and chronic complications were significantly increased (P <0.01). Conclusion: IL-6 may be involved in the pathological changes of diabetes, and can be used as an index to judge the condition clinically.