目的:探讨复苏周期单囊胚和双囊胚移植对患者妊娠结局的影响。方法:回顾性分析行囊胚冷冻-复苏患者2 021例,其中单囊胚复苏移植组(A组)326例,双囊胚复苏移植组(B组)1 695例。比较单/双囊胚复苏移植对患者临床结局的影响及新生儿情况分析。结果:A组胚胎着床率、临床妊娠率、早产率、多胎率、低体质量儿率分别显著低于B组(P<0.05);A组早期流产率、新生儿体质量、身长以及Apgar评分均显著高于B组(P<0.05)。结论:单囊胚移植能够明显降低多胎率及产科风险。 OBJECTIVE: To investigate the effect of single and double blastocyst transfer during pregnancy on pregnancy outcomes. Methods: A total of 2 021 cases of frozen blastocyst were enrolled in this study. Among them 326 cases of single blastocyst resuscitation (A group) and 1 695 cases of double-blastocyst resuscitation (B group) were retrospectively analyzed. The effect of single / double blastocyst resuscitation on the clinical outcome of the patients and the analysis of newborns. Results: The embryo implantation rate, clinical pregnancy rate, preterm birth rate, multiple birth rate and low birth weight in group A were significantly lower than those in group B (P <0.05). In group A, the abortion rate, neonatal body weight, The scores were significantly higher than those in group B (P <0.05). Conclusion: Single blastocyst transplantation can significantly reduce the multiple birth rate and obstetric risk.