尘肺病的诊断目前主要依据临床表现、X射线胸片和肺功能等,这些改变均是以肺组织纤维化为基础,一旦形成即不可逆转。虽然目前无法用单一的机制来解释矽肺发病的机制,但公认的是在起始阶段共同有炎症因子的参与,并介导肺纤维化的形成。一氧化氮(NO)是20世纪80年代初被发现的生物 The diagnosis of pneumoconiosis is mainly based on clinical manifestations, X-ray and pulmonary function, these changes are based on lung tissue fibrosis, once formed that is irreversible. Although it is not possible to explain the mechanism of silicosis with a single mechanism at present, it is recognized that inflammatory factors are involved in the initial phase and mediate the formation of pulmonary fibrosis. Nitric oxide (NO) was discovered in the early 1980s