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目的:探讨准分子激光原位角膜磨镶术(LASIK)术中负压吸引时间对角膜瓣厚度和直径的影响。方法:根据负压吸引时间的不同将60只猪眼随机分为3组:组1(10s)、组2(20s)和组3(30s),使用法国产MoriaM2型角膜板层刀分别吸引角膜10s,20s和30s后切削角膜瓣,利用角膜超声测厚仪测量角膜瓣厚度,应用镀铬游标卡尺测量角膜瓣直径。结果:组1、2和3角膜瓣厚度分别为146.05±13.46,157.35±18.95和169.25±21.02μm,各组间比较有显著性差异(P=0.001)。各组的平均角膜瓣直径分别为8.63±0·19mm(组1,10s),8.89±0.24mm(组2,20s)和9.06±0·18mm(组3,30s)。各组间比较有显著性差异(P<0·01)。结论:LASIK术中随着负压吸引时间的延长,角膜瓣厚度和直径均增加。
Objective: To investigate the effect of negative pressure on the thickness and diameter of corneal flap during laser in situ keratomileusis (LASIK). Methods: Sixty swine eyes were randomly divided into three groups according to the time of vacuum suction: group 1 (10s), group 2 (20s) and group 3 (30s). The French MoriaM2 corneal lamellar knife was used to draw the cornea The corneal flap was cut after 10s, 20s and 30s. Corneal flap thickness was measured by corneal ultrasonic thickness gauge. Corneal flap diameter was measured by chrome-plated caliper. Results: The thickness of corneal flap in groups 1, 2 and 3 were 146.05 ± 13.46, 157.35 ± 18.95 and 169.25 ± 21.02μm, respectively. There was significant difference between the groups (P = 0.001). The average corneal flap diameters in each group were 8.63 ± 0.19mm (group 1,10s), 8.89 ± 0.24mm (group 2,20s) and 9.06 ± 0.18mm (group 3,30s), respectively. There was significant difference between the groups (P <0.01). CONCLUSION: The thickness and diameter of corneal flap increase with the extension of negative pressure during LASIK.