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目的：评价国产特比萘芬治疗头癣的疗效及安全性，探索最佳给药方案。方法：头癣患者随机分成三组，A组连服2周，B组连服4周，C组连服1周后间隔2周再连服1周，4周治疗中不口服特比萘芬时给安慰剂，按体重给药，于第8周末评价疗效及安全性。结果：76例可评价患者分离的病原菌主要包括犬小孢子菌48株（62．3％）、须癣毛癣菌24株（31．2％）。于8周末评价时，治愈率分别为64％、889％和83．3％。只见轻微副作用。结论：口服国产特比萘芬治疗头癣疗效高、安全性好、患者耐受性好，连续服药1周后间隔2周再连续服药1周，为我们的推荐方案。
Objective: To evaluate the efficacy and safety of domestic terbinafine in the treatment of tinea capitis and to explore the optimal dosage regimen. Methods: Patients with tinea capitis were randomly divided into three groups. Group A received 2 weeks of continuous treatment. Group B received 4 weeks of continuous treatment. Group C received 1 week of intermittent treatment for 1 week and then received 1 week of continuous treatment. Patients in group C did not receive terbinafine 4 weeks after treatment. Placebo, administered on a weight basis, evaluated efficacy and safety at the end of the 8th week. Results: The pathogenic bacteria isolated from 76 evaluable patients mainly consisted of 48 (64.3%) of Microsporum canis and 24 (31.2%) of Trichophyton mentagrophytes. At the 8th weekend, the cure rates were 64%, 889% and 83.3%, respectively. I saw slight side effects. Conclusion: Terbinafine oral homeopathic treatment of psoriasis with high efficacy, good safety, patient tolerance, continuous medication for 1 week after 2 weeks and then take a continuous medication for 1 week, is our recommended program.