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西米替丁(Cimetidine简称Cim)自七十年代问世以来,临床主要用于消化性溃疡、上消化道出血的治疗.近年来临床实践发现,它对其他多种疾病均有治疗作用,应用日益广泛,综述如下.1 病毒性疾病1.1 带状疱疹Cim有免疫保护、止痒及抗病毒作用.带状疱疹是由疱疹性病毒感染所至的皮肤病.据国外报告,Spay用Cim治疗21例带状疱疹,19例显效,2例无效.国内有人用Cim治疗带状疱疹53例,每次200mg口服,每日三次,睡前加服200mg,结果均获痊愈(皮疹消退或残留痂皮、神经痛消失).平均疗程3.5天.一般24小时后即见效,治疗过程中无一例加剧.也未见不良反应.Bense1987年用800～1200mg/d,分2～3次口服,治疗2例带状疱疹,认为不仅见效快(即用药2～3天症状缓解).且能抑制新的疱疹出现.1.2 水痘 鉴于水痘与带状疱疹均是由水痘带状疱疹病毒引起的同一病原体的两种不同疾病,由此推理认为它对水痘亦应有效.国内有人用Cim治疗85例水痘患者(15mg/(kg.d),分3次口服,3天为一疗程),平均治疗2天即获痊愈.服药后1～2天体温正
Cimetidine (Cimetidine referred to as Cim) since the advent of the seventies, the clinical mainly for peptic ulcer, upper gastrointestinal bleeding treatment .In recent years, clinical practice found that it has a variety of other diseases have therapeutic effect, increasingly Widespread, summarized as follows.1 Viral diseases 1.1 shingles Cim immune protection, antipruritic and anti-viral effect.Zoster herpes virus is infected by the skin disease.According to foreign reports, Spay with Cim treatment of 21 cases Shingles, 19 cases markedly effective, 2 cases ineffective. Some people use Cim treatment of shingles in 53 cases, each 200mg orally, three times a day, plus 200mg before going to bed, the results were cured (rash subsided or residual crust, Neuralgia disappeared.) The average course of treatment is 3.5 days, usually effective after 24 hours, no one exacerbated in the course of treatment, and no adverse reactions .Bense1987 800 ~ 1200mg / d, 2 to 3 times orally, the treatment of 2 cases with Herpes zoster, that not only effective (that is, medication 2 to 3 days to relieve symptoms) and can inhibit the emergence of new herpes.1.2 varicella varicella and shingles are varicella zoster virus caused by the same two different pathogens The disease, from which reason it is thought to chickenpox also Effective domestic Cim someone treat 85 patients with varicella (15mg / (kg.d), orally 3 times, 3 days for treatment), the average treatment were recovered two days i.e. 1 to 2 days after taking the positive temperature