药物性肝损害是常见的药物不良反应之一。随着新药的不断开发应用以及各种药物的联合应用增多,药物性肝损伤的发生率不断增加,有1000种以上的药物与药物性肝损害有关。由于药物性肝损伤的临床表现无特异性,且缺乏有效的特异性实验室检查,临床上易引起误诊及漏诊。现就药物性肝病(DILD)的临床特点及误诊原因等予以综述,以加深对DILD的认识,为预防和早期治疗该病提供参考。 Drug-induced liver damage is one of the common adverse drug reactions. With the continuous development and application of new drugs and the joint application of various drugs increased, the incidence of drug-induced liver injury continues to increase, with more than 1,000 kinds of drugs and drug-induced liver damage. Due to the non-specific clinical manifestations of drug-induced liver injury, and the lack of effective specific laboratory tests, clinically easy to cause misdiagnosis and missed diagnosis. The clinical features and the causes of misdiagnosis of drug-induced liver disease (DILD) are reviewed in order to deepen the understanding of DILD and provide a reference for the prevention and early treatment of the disease.