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目的 :分析循环免疫复合物 (CIC)在有 /无近期感染史的脑梗死 (CI)病例中的特征。方法 :测定 18例有近期感染史和 2 8例无近期感染史共 46例动脉硬化性脑梗死病例发病初期和恢复期及 12 4例正常对照的 CIC、补体 C1q、C3,脑梗死病例按有 /无感染史分组做发病初期测定值比较 ,并与正常对照测定值比较 ,同时与恢复期测定值比较。结果 :有 /无近期感染史脑梗死发病初期 CIC均高于正常对照组〔(6 .70± 4.2 7) m g/dl〕,且有感染史组梗死初期 CIC〔(19.6 9± 15 .18) m g/dl〕高于无感染史组〔(14.40± 10 .12 ) m g/dl〕。 C1q两组发病初期测定值〔(0 .15±0 .0 4) g/L ,(0 .14± 0 .0 5 ) g/L〕低于正常对照〔(0 .2 0± 0 .0 4) g/L〕,恢复期回升。 C3发病初期有 /无感染史组均低于正常对照组〔(1.71± 0 .5 7) g/L〕,有感染史组〔(1.39± 0 .72 ) g/L〕高于无感染史组〔(1.0 0± 0 .45 ) g/L〕,恢复期回升不明显。结论 :CIC升高可能与感染有关 ,CIC升高可能参与了脑梗死的免疫损伤过程。
PURPOSE: To analyze the characteristics of circulating immune complexes (CICs) in patients with a history of cerebral infarction (CI) with or without recent infection. Methods: 18 cases of recent history of infection and 28 cases of no recent history of infection were detected in 46 cases of atherosclerotic cerebral infarction in the early onset and recovery and 12 4 cases of normal control CIC, complement C1q, C3, cerebral infarction according to / No history of infection subgroups to do the early onset of the measured values compared with the normal control measured values at the same time, compared with the recovery of measured values. Results: The CIC in the early stage of cerebral infarction with / without recent infection was significantly higher than that in the control group [(6.770 ± 4.27) mg / dl], and the CIC (19.6 9 ± 15.18) mg / dl] higher than those without infection 〔(14.40 ± 10.12) mg / dl〕. C1q early onset of the measured values [(0 .15 ± 0. 04) g / L, (0.14 ± 0. 05) g / L〕 lower than the normal control 〔(0 2 0 ± 0. 0 4) g / L〕 recovery recovery. Patients with and without history of onset of C3 were significantly lower than those in the control group [(1.71 ± 0.57) g / L〕 (1.39 ± 0.72 g / L, respectively) Group [(1.0 0 ± 0.45) g / L〕, recovery recovery is not obvious. CONCLUSION: Elevated CIC may be related to infection. Elevated CIC may be involved in the process of immune damage in cerebral infarction.