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目的 :分析慢性乙型肝炎患者抗病毒治疗的效果及其影响因素。方法 :选取2012年3月至2015年6月期间来我院接受治疗的乙型肝炎患者90例作为本次研究对象,根据治疗方式的不同,将90例患者随机分为研究组与对照组,每组各45例患者,对照组的患者采取常规的方式进行治疗,研究组则为患者提供抗病毒治疗;治疗结束后,对两组患者的临床效果进行观察与比较。结果 :通过不同药物治疗后,研究组患者ALT恢复正常为43例(95.56%),HBe Ag转阴为41例(91.11%);对照组患者ALT恢复正常为39例(86.67%),HBe Ag转阴为36例(80.00%);组间数据差异明显,(p<0.05),具有统计学意义。结论 :抗病毒药物治疗慢性乙肝患者的临床效果显著,治疗效果明显高于一般的保肝药物,值得在临床上广泛推广及使用。
Objective: To analyze the effect of antiviral therapy in chronic hepatitis B patients and its influential factors. Methods: Ninety patients with hepatitis B treated in our hospital from March 2012 to June 2015 were selected as the study subjects. According to the different treatment methods, 90 patients were randomly divided into study group and control group, Each group of 45 patients, the control group of patients taking the usual way of treatment, the study group provides the patient with antiviral therapy; after treatment, the clinical effect of the two groups were observed and compared. Results: After treatment with different drugs, ALT returned to normal in 43 cases (95.56%) and HBe Ag in 41 cases (91.11%) in the study group, 39 cases (86.67%) returned to normal in the control group, HBeAg 36 patients (80.00%) had negative conversion. The data of the two groups showed significant difference (p <0.05), which was statistically significant. Conclusion: The clinical efficacy of antiviral drugs in the treatment of chronic hepatitis B patients is remarkable, and the therapeutic effect is obviously higher than that of general liver-protecting drugs. It is worth widely popularized and used clinically.