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目的报道重庆主城首例输入性黑热病,探讨黑热病的实验室诊断,降低误诊率。方法分析1例黑热病病例的临床资料及骨髓中利杜体的形态特点,结合rk39免疫层析试纸条检测。结果该患者有黑热病疫区生活史,有不规则发热、脾大、白细胞计数降低、贫血、血小板减少等症状,骨髓检查显示骨髓增生活跃,吞噬细胞内外可见杜氏利什曼原虫无鞭毛体,rk39免疫层析试纸条检测阳性,因此确诊为黑热病。结论根据患者的流行病学资料、临床表现和实验室检查结果,该病例确诊为黑热病。
Objective To report the first case of imported kala azar in the main city of Chongqing to investigate the laboratory diagnosis of kala-azar and reduce the rate of misdiagnosis. Methods The clinical data of 1 case of kala-azar and the morphological characteristics of Lepidoptera in bone marrow were analyzed, and the results of rk39 immunochromatographic test strips were analyzed. Results The patient had a history of SARS, irregular fever, splenomegaly, white blood cell count, anemia, thrombocytopenia and other symptoms. Bone marrow examination showed active myeloproliferation, leishmania donovani body inside and outside the phagocyte, rk39 Immunochromatographic strip test positive, so diagnosed as kala-azar. Conclusion According to the patient’s epidemiological data, clinical manifestations and laboratory findings, the case was diagnosed as kala-azar.