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尿β_2-微球蛋白(β_2M)定量测定是评价肾小管重吸收功能损害的敏感指标。近几年来,国外已应用于镉等重金属的职业接触或环境接触所致中毒性肾脏损害的流行病学调查和临床研究,但国内尚未有这方面的报道。为便于今后开展职业性与环境镉危害的调查和慢性镉中毒的临床诊断工作,我们对北京市无过量镉等重金属接触史的健康居民作了尿中β_2M含量的初步调查,现将结果加以报道,以供参考。
The quantitative determination of urinary β_2-microglobulin (β_2M) is a sensitive index to evaluate the renal tubular reabsorption dysfunction. In recent years, foreign countries have applied cadmium and other heavy metals occupational exposure or environmental exposure caused by toxic kidney damage epidemiological investigations and clinical studies, but not yet reported in this area. To facilitate the future investigation of occupational and environmental cadmium hazards and the clinical diagnosis of chronic cadmium poisoning, we conducted a preliminary survey on the urinary β 2M content of healthy residents with no history of heavy metal exposure such as cadmium in Beijing. The results are reported ,for reference.