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为了解氧自由基在卡那霉素耳中毒中的可能作用,作者采用硫代巴比妥酸(TBA)荧光比色法测定了实验性卡那霉素耳中毒时豚鼠耳蜗组织中氧自由基反应代谢产物丙二醛(MDA)的含量变化,以探讨卡那霉素耳中毒与自由基产生的关系。 1 材料和方法 实验用白色健康豚鼠80只,雌雄不
To understand the possible role of oxygen free radicals in kanamycin ototoxicity, the authors used thiobarbituric acid (TBA) fluorescent colorimetric method to determine the oxygen free radicals Reactive metabolites malondialdehyde (MDA) content changes in order to explore the relationship between kanamycin ototoxicity and free radicals. 1 Materials and Methods Experimental white healthy guinea pigs 80, male and female not