不可逆慢性支气管炎病人(慢支)常给口服氨茶硷来治疗而缺乏有对照的疗效研究。著者等应用肺量测定法来测定不可逆慢支病人,经过口服氨茶硷对其肺功能的效果。21例男性稳定的慢支病人,通过病史,第一秒呼出率(FEV_1/FVC)<65%和吸入二羟苯基异丙氨基乙醇后症状无改善来确定诊断。本组病人平均年龄为61岁,平均第一秒呼出率为51%。在测定基础参数前5天,停用一切扩张支气管药物,测定时血清氨茶硷水平等于零。测定基础肺量之后,接着连续口服 Irreversible Chronic bronchitis patients (chronic bronchitis) often give oral aminophylline to treat without a controlled study of efficacy. The authors used spirometry to determine the effect of oral aminophylline on lung function in patients with irreversible chronic bronchitis. Twenty-one patients with stable chronic bronchitis were diagnosed by their medical history, first-second exhalation rate (FEV 1 / FVC) <65%, and no improvement in symptoms after inhaled dihydroxyphenyl isopropylaminoethanol. The average age of patients in this group was 61 years, the average first second call rate was 51%. 5 days before the determination of the basic parameters, disable all the expansion of bronchial drugs, measured serum aminophylline level is equal to zero. After the determination of basal lung volume, followed by continuous oral administration