在儿童,生后获得性弓浆虫感染较常见,一般症状轻微或无症状,但防御功能低下者则较重,常可致死。本病及早治疗预后良好,由于临床上常把其症状误为伴发病、药物的并发症、或其他各类感染所致,常延误诊断、贻误治疗时机。文献中儿童因免疫功能低下患暴发性弓浆虫病极少。作者报告一例:女,15岁,白种人。入院前4个月确诊为急性成淋巴细胞性白血病(ALL),给予强的松、长春新碱、正定霉素及L-天冬酰胺酶作诱导治疗,同时鞘内用阿糖胞苷、氨甲喋呤及头颅放疗以预防中枢神经系白血病。骨髓象经诱导期缓解后,用阿糖胞苷、6-巯基嘌呤及环磷酰胺作联合化疗。患者平素喜欢家兔,否认猫接触史,无食未煮熟肉史。入院前一周发热39℃,偶有轻度头痛、嗜眠。入院时查口温38.4℃,有脱发,余无显著异常。实验室查嗜中性白细胞300/mm~3。作细菌培养后,施 In children, acquired acquired Toxoplasma gondii infection is more common, the general symptoms of mild or asymptomatic, but defensive dysfunction were heavier, often lethal. Early treatment of this disease is a good prognosis, often clinically mistaken for its symptoms associated with the disease, drug complications, or other types of infections, often delayed diagnosis, delaying the timing of treatment. Children in the literature suffer from fulminant boletosis due to low immunocompromisedness. The author reports an example: Female, 15 years old, Caucasian. Four months prior to admission, acute lymphoblastic leukemia (ALL) was diagnosed, and prednisone, vincristine, naringin and L-asparaginase were given for induction therapy. At the same time, cytarabine, methotrexate And cranial radiotherapy to prevent central nervous system leukemia. Bone marrow after induction of remission, with cytarabine, 6 - mercaptopurine and cyclophosphamide for combined chemotherapy. Patients usually like rabbits, denied the history of cat contact, no food cooked meat history. One week before admission fever 39 ℃, occasional mild headache, somnolence. Check mouth temperature 38.4 ℃ admission, hair loss, I no significant abnormalities. Laboratory investigation neutrophil 300 / mm ~ 3. After bacterial culture, Shi