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目的探讨奥美拉唑治疗急性农药中毒并上消化道出血的临床疗效。方法将2008年2月-2012年12月间我院100例急性农药中毒并上消化道出血患者随机将其分成两组各50例,对照组采用西咪替丁治疗,观察组采用奥美拉唑治疗,每隔2h行胃液潜血实验,并记录潜血转阴时间。比较两组疗效。结果观察组胃液潜血转阴时间明显低于对照组(P<0.05),治疗有效率明显高于对照组(P<0.05)。结论奥美拉唑治疗急性农药中毒并上消化道出血临床疗效显著,能明显减少患者胃液潜血转阴时间,值得临床应用。
Objective To investigate the clinical efficacy of omeprazole in the treatment of acute pesticide poisoning and upper gastrointestinal bleeding. Methods 100 cases of acute pesticide poisoning and upper gastrointestinal bleeding in our hospital from February 2008 to December 2012 were randomly divided into two groups of 50 cases each and the control group was treated with cimetidine. Azole treatment, gastric occult blood test every 2h, and record the occult blood turn negative time. Compare the two groups curative effect. Results The gastric occult blood in the observation group was significantly lower than that in the control group (P <0.05), and the effective rate of treatment was significantly higher than that of the control group (P <0.05). Conclusion Omeprazole treatment of acute pesticide poisoning and upper gastrointestinal bleeding clinical significant effect, can significantly reduce the gastric occult blood in patients with negative time, it is worth clinical application.