1例73岁男性因急性脑梗死合并癫痫、高血压、支气管炎、冠状动脉粥样硬化性心脏病、心房颤动入院,先后给予甘露醇、甘油果糖,缬沙坦、富马酸比索洛尔、马来酸桂哌齐特、奥扎格雷钠、哌拉西林钠他唑巴坦钠、头孢他啶、依替米星、阿托伐他汀钙。用药前丙氨酸转氨酶(ALT)18 U/L,天冬氨酸转氨酶(AST)25 U/L。第13天,ALT 243 U/L,AST 111 U/L。停用马来酸桂哌齐特并给予葡醛内酯、谷胱甘肽。停用马来酸桂哌齐特第7天,ALT36 U/L,AST 27 U/L。 A 73-year-old man was hospitalized for acute cerebral infarction with epilepsy, hypertension, bronchitis, coronary heart disease and atrial fibrillation. He was given mannitol, glycerol fructose, valsartan, bisoprolol fumarate, Cinepazide maleate, ozagrel sodium, piperacillin sodium tazobactam sodium, ceftazidime, etimicin, atorvastatin calcium. Before treatment, alanine aminotransferase (ALT) 18 U / L, aspartate aminotransferase (AST) 25 U / L. On day 13 ALT 243 U / L, AST 111 U / L. Cinepazide maleate was discontinued and glucurolactone and glutathione were given. On day 7 of cinepazide maleate, ALT 36 U / L and AST 27 U / L were discontinued.