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目的:探讨中线恶性肉芽肿(中线恶网)的诊断、治疗及预后因素。方法:病例均经过放射治疗,其中9例配合化疗。结果:中线恶性肉芽肿多为结外侵犯的外周T细胞淋巴瘤,首选的治疗方法是局部放射治疗,本组病例1a、3a、5a和10a生存率分别为89.2%、72.1%、63.5%和40.0%。患者年龄、有无发热、病变范围、是否淋巴结受侵犯是影响生存率的重要因素。病程和本组观察的放射治疗剂量对生存率无明显影响。结论:以下几个因素对预后有影响:年轻者预后差;有发热者预后差;病变范围广泛者预后差;有淋巴结转移者预后差。
Objective: To investigate the diagnosis, treatment and prognosis of median malignant granuloma (median nevus). Methods: All cases were treated by radiotherapy, including 9 cases with chemotherapy. Results: The median malignant granuloma was mostly extranodal peripheral T-cell lymphoma. The preferred treatment was local radiotherapy. The survival rates of cases 1a, 3a, 5a and 10a were 89.2%, 72.1%, 63.5% and 40.0%. Patient age, with or without fever, the extent of the lesion, whether the invasion of lymph nodes is an important factor affecting the survival rate. The course of the disease and the observed radiotherapy dose had no significant effect on the survival rate. Conclusion: The following factors have an impact on the prognosis: poor prognosis in young people; poor prognosis in patients with fever; extensive prognosis of patients with poor prognosis; poor prognosis with lymph node metastasis.