我院自1985年以来应用小剂量心得安加异搏定治疗顽固性心绞痛160例,取得较好效果,报道如下:一、临床资料(一)治疗对象 用随机双盲法分为治疗组与对照组,均为住院病人.治疗组80例,男60例,女20例.年龄44～76岁,平均年龄56岁.80例患者均系用硝酸甘油、心痛定和消心痛治疗无效而收住院的病人,发作时心电图均有缺血改变和ST—T的变化.按临床分型,变异型心绞痛40例,伴有ST段抬高的劳力型心绞痛10例;梗塞后早期心绞痛30例,均有冠状动脉痉挛因素存 Our hospital since 1985, the application of low-dose experience Angavirin set treatment of refractory angina in 160 cases, and achieved good results, reported as follows: First, the clinical data (a) treated with double-blind randomized treatment group and control Group, all inpatients.The treatment group of 80 cases, 60 males and 20 females.Ages ranging from 44 to 76 years, mean age 56 years.80 patients were treated with nitroglycerin, Of the patients, the onset of electrocardiogram changes were ischemic and ST-T changes.According to clinical classification, variant angina pectoris 40 cases, accompanied by ST segment elevation labor angina 10 cases; early post-infarction angina 30 cases, both Coronary artery spasm factors exist