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本文应用ABC-ELISA法观察了58例常规尿检查正常的高血压患者尿微量蛋白含量,并与常规ELISA进行了比较。结果表明,本组病人中53.4％患者有微量蛋白尿存在。对12例尿微量蛋白增高的病人,于血压降至正常后30天复查,各种尿微量蛋白较前明显减少,其中7例恢复至正常范围,结果证明,此种方法的灵敏度高于普通ELISA,应用本方法动态观察高血压患者尿中微量蛋白有助于判断肾脏损害的轻重和评价疗效。
ABC-ELISA method was used to detect urinary microalbuminuria in 58 cases of normal hypertensive patients with normal urinalysis, and compared with conventional ELISA. The results showed that 53.4% of patients in this group had microalbuminuria. In 12 cases of patients with elevated urinary microalbuminuria, blood pressure was reduced to normal 30 days after the review, a variety of urine micro-protein was significantly reduced, of which 7 patients returned to normal range, the results show that the sensitivity of this method is higher than normal ELISA , The application of this method to dynamically observe the urine microalbuminuria in patients with hypertension can help determine the severity of renal damage and evaluate the efficacy.