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为制备高效环保仿生材料,以Na_2HPO_4和Ca(NO_3)_2·4H_2O为原料,采用化学沉淀法合成羟基磷灰石粉体,将粉体超声分散在壳聚糖醋酸溶液中,通过溶液共混和磁力搅拌的方法制备羟基磷灰石-壳聚糖(hydroxyapatite-chitosan,HA-CS)悬浮液.采用旋涂法在不锈钢304基材表面涂覆HA-CS悬浮液,分别在25℃和37℃条件下干燥12 h成膜.将两种HA膜样分别通过X射线衍射、傅立叶变换红外光谱、扫描电子显微镜、X射线能量色散仪和电子拉力机进行测试.结果表明,HA-CS复合材料的拉伸强度达(69.04±1.21)MPa;复合膜结晶度好,黏结致密,无分解,无杂质;旋涂法能更好的使HA均匀分散在CS中,减少HA微粒的团聚和游离;与25℃相比,37℃条件下干燥HA膜有助于HA与CS更多更好地结合,使制得的HA-CS复合膜具有优良性能.为HA-CS复合膜附着金属植入物在人体环境内成功生长提供理论参考.
In order to prepare highly efficient and environmentally friendly biomimetic materials, the hydroxyapatite powder was synthesized by chemical precipitation using Na_2HPO_4 and Ca (NO_3) _2 · 4H_2O as raw materials. The powders were dispersed ultrasonically in chitosan acetate solution and mixed by solution and magnetic force Hydroxyapatite-chitosan (HA-CS) suspension was prepared by a stirring method.The HA-CS suspension was coated on the surface of stainless steel 304 by spin-coating method, respectively at 25 ℃ and 37 ℃ And then dried for 12 h to form a film.The two HA films were respectively tested by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive X-ray spectrometer and electronic tensile testing machine.The results showed that the HA-CS composite (69.04 ± 1.21) MPa; the crystallinity of the composite film is good, the bond is dense, no decomposition, no impurities; spin coating method can better disperse HA evenly in the CS to reduce the agglomeration and dissociation of the HA particles; ℃, the drying of HA film at 37 ℃ will help HA and CS to bind more and better, which will make the prepared HA-CS composite film have better performance.For HA-CS composite film attached to metal implants in the human body Provide a theoretical reference for the successful growth within the environment.