儿童含麻疹成分疫苗初免及时接种率及其影响因素的病例对照研究

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目的了解中山市9月龄~2岁儿童含麻疹成分疫苗(Measles Containing Vaccine,MCV)初免及时接种率及其影响因素,为制定防控策略提供科学依据。方法采用二阶段分层抽样方法,调查中山市200名儿童及其监护人的人口学特征、MCV初免情况、监护人知识态度以及预防接种服务,分析MCV初免及时接种率及其影响因素。结果儿童MCV初免接种率和及时接种率分别为99.5%和65.3%,二分类Logistic回归分析显示:儿童生病、儿童同谁生活、预防接种重要吗、是否知道麻疹初免月龄是儿童MCV初免及时率的影响因素(均为P<0.05),生病儿童MCV初免不及时的风险为不生病者的3.829(95%CI:1.836~7.986)倍,儿童同老人生活MCV初免不及时的风险为同父母生活者的3.156(95%CI:1.196~8.328)倍,家长认为预防接种不重要的儿童MCV初免不及时的风险为家长认为预防接种重要者的5.953(95%CI:1.755~20.195)倍,家长不知道麻疹初免月龄的儿童MCV初免不及时的风险为家长知道者的2.297(95%CI:1.080~4.885)倍。结论中山市儿童MCV初免接种率较高,但及时接种率偏低,应采取针对性措施提高MCV初免及时接种率。 Objective To investigate the timely vaccination rate and its influencing factors of Measles Containing Vaccine (MCV) in children aged 9 months to 2 years old in Zhongshan City, and to provide a scientific basis for making prevention and control strategies. Methods Two-stage stratified sampling method was used to investigate the demographic characteristics, MCV initial immunization status, guardian’s knowledge and attitude and vaccination services of 200 children and their guardians in Zhongshan City. The timely vaccination rate and its influential factors were analyzed. Results The initial vaccination rate and timely vaccination rate of MCV in children were 99.5% and 65.3% respectively. Logistic regression analysis showed that children were sick, children were living with whom and vaccination was important. (P <0.05). The untimely risk of MCV in sick children was 3.829 (95% CI: 1.836 ~ 7.986) times lower than those in non-sick children (95% CI: 1.196-8.328) times higher than those living with parents. The risk of premature infant MCV missed by parents in vaccinated insomnia was 5.953 (95% CI: 1.755 ~ 20.195) times. Parents were unaware of 2.297 (95% CI: 1.080 ~ 4.885) times the risk of premature MCV premature death in children with PMV. Conclusion The MCV vaccination rate in Zhongshan children is high, but the timely vaccination rate is low. Targeted measures should be taken to improve the MCV vaccination rate in time.
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