论文部分内容阅读
中西医结合治疗胆道感染,一般以疏肝利胆、清热去湿为主,在临床上收到一定效果。本文是根据临床实验研究的结果,比较常用的中药方剂、葡糖二酸-1,4-内酯、葡糖醛酸内酯、甘草流浸膏对手术后胆汁中β-葡糖醛酸苷酶活性的影响。结果发现,在体外试验,葡糖二酸-1,4-内酯对β-葡糖醛酸苷酶活性抑制最显著,而葡糖醛酸内酯(肝泰乐)则有促进作用,其他二者作用不明显。口服后2小时,胆汁中β-葡糖醛酸苷酶均有一定程度的抑制,其中以肝泰乐和甘草流浸膏的作用较明显,葡糖二酸-1,4-内酯次之,本实验中所用之中药方剂较弱。但在长时间服用中药的病例,亦见对胆汁中β-葡糖醛酸苷酶活性的明显抑制。文中讨论肝泰乐和甘草流浸膏的作用,及其在中西医结合治疗胆道感染的意义。
Integrative Medicine for the treatment of biliary tract infections, generally Shugan gallbladder, heat dampness-based, clinically received a certain effect. This article is based on the results of clinical trials, the more commonly used traditional Chinese medicine prescription, glucosidic acid -1,4-lactone, glucuronolactone, licorice extract on postoperative bile β-glucuronide Effect of enzyme activity. The results showed that glucuronyl 1,4-lactone had the most significant inhibitory effect on β-glucuronidase activity in vitro and glucuronolactone The role of both is not obvious. 2 hours after oral administration, β-glucuronidase in bile has a certain degree of inhibition, of which the role of liver and licorice extract more obvious, glucaric acid -1,4-lactone followed The Chinese medicine used in this experiment is weak. However, in the long period of taking traditional Chinese medicine cases, also see the β-glucuronidase activity was significantly inhibited. The article discusses the role of liver and licorice extract, and its significance in the treatment of biliary tract infection with integrated traditional Chinese and Western medicine.