mad—overexpression down regulates the malignant growth and p53 mediated apoptosis in human hepatocel

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Mad protein has been shown as an antagonist of cMyc protein in some cell lines.The effect of Mad protein to the malignant phenotype of human hepatoma BEL-7404 cell line was investigated experimentally.An eukarryotic vector pCDNA Ⅲ containing full ORF frag
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