人工晶体（ＩＯＬ）植入后间隔时间不等，摘取患者眼、兔眼和小鼠腹膜外间隙内的ＩＯＬ，利用光镜和电镜进行ＩＯＬ表面膜和细胞学比较观察。其中，人眼ＩＯＬ表面的反应膜最轻微；巨噬细胞和多核巨细胞数量极少；几乎未见淋巴细胞反应。２０只家兔分为实验组和对照组，经７ｄ、２０ｄ、３４ｄ和７４ｄ组织病理学比较观察，两组并无差别。结果提示，植入的ＩＯＬ均仅引起轻度异物反应。 Intraocular lenses (IOLs) were implanted at different time intervals. The IOLs in the peritoneal space of patients eyes, rabbit eyes and mice were harvested. The IOL surface and cytology were observed by light and electron microscopy. Among them, the human eye IOL surface reaction film is the youngest; macrophages and multinucleated giant cells in very small number; almost no lymphocyte reaction. Twenty rabbits were divided into experimental group and control group. After 7d, 20d, 34d and 74d histopathological observation, there was no difference between the two groups. The results suggest that implanted IOLs only cause mild foreign body reactions.