目的 :了解血液灌流治疗婴幼儿毒鼠强中毒的疗效。方法 :采用回顾性病例对照分析的方法 ,比较 16例血液灌流和 10例保守治疗毒鼠强中毒婴幼儿临床疗效差异。结果 :与保守治疗相比 ,血液灌流治疗可显著缩短患儿抽搐、昏迷和住院时间 ,改善昏迷评分。血液灌流后患儿毒鼠强浓度下降 ,改良Glasgow昏迷评分提高。结论 :血液灌流是治疗婴幼儿毒鼠强中毒的有效方法。 Objective: To understand the therapeutic effect of hemoperfusion on tetramine poisoning in infants and young children. Methods: A retrospective case-control analysis was used to compare the clinical efficacy of 16 hemoperfusion and 10 conservative treatment of tetramine poisoning in infants and young children. Results: Compared with conservative treatment, hemoperfusion treatment significantly reduced convulsions, coma and hospital stay in children and improved coma score. Strong concentrations of tetramine poisoning in children after hemoperfusion, improved Glasgow coma score increased. Conclusion: Hemoperfusion is an effective method to treat tetramine poisoning in infants and young children.