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在放射免疫分析方法中,一个完善的分离系统应该具备以下优点:复分误差小、操作简便、分离迅速、反应平衡不受干扰、能有效地分离免疫反应中产生的结合抗原和游离抗原。常规的液相分离方法尚不能同时满足这些要求。1971年Hollander首先报道
In the radioimmunoassay method, a perfect separation system should have the following advantages: small error, simple operation, rapid separation, reaction equilibrium without interference, can effectively separate the immune response produced by the combination of antigen and free antigen. Conventional liquid phase separation methods can not simultaneously meet these requirements. Hollander first reported in 1971