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对探讨乙肝疫苗阻断母婴传播的效果,我们对HBsAg 和 HBeAg 阳性孕妇所生的新生儿65例,用酵母重组基因疫苗与血源疫苗阻断乙肝母婴传播的免疫效果进行了研究。设实验组5个、实验对照组2个和空白对照组1个。研究对象于出生时,1、3、6、9、12月随访,采血用 RIA 法 Abbott 药合检测 HBsAg、抗-HBs。判断标准 P/N≥10为阳性,HBsAg 阳性出现时间≥6个月者为 HBsAg
To investigate the effect of Hepatitis B vaccine in blocking mother-to-infant transmission, we studied 65 neonates born to HBsAg and HBeAg-positive pregnant women, and studied the immunogenicity of recombinant hepatitis B vaccine and blood-borne vaccine to block the transmission of hepatitis B virus. There were 5 experimental groups, 2 experimental control groups and 1 blank control group. At the time of birth, the subjects were followed up for 1, 3, 6, 9 and 12 months. Blood was collected for detection of HBsAg and anti-HBs by RIA Abbott. To determine the standard P / N ≥ 10 is positive, HBsAg positive appearance of ≥ 6 months were HBsAg