６０例择期行纤维结肠镜检查病人，男３７例，女２３例，年龄１６．７岁～４３．４岁，均无重大肝、肾、心、肺疾患。随机分为P、F、K３组。３组病例的性别、年龄均无显著差异。所有患者麻醉前半小时均肌肉注射阿托品０．５mg。P组单用异丙酚，以异丙酚１．５mg／kg～２．５mg Sixty patients underwent elective colonoscopy, including 37 males and 23 females, ranging in age from 16.7 to 43.4 years without major liver, kidney, heart and lung diseases. Randomly divided into P, F, K3 group. There was no significant difference in gender and age between the three groups. All patients were anesthetized half an hour before intramuscular injection of atropine 0.5mg. P group with propofol, propofol 1.5mg / kg ~ 2.5mg