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报告1例原发性皮肤黏液癌.患者男,65岁.左颧部外上方结节1年余.皮肤科检查:左侧颧部一1.5 cm×1 cm红色结节,突出于皮面,界限清楚,表面光滑,可见毛细血管扩张,与周围组织无粘连.皮损组织病理检查:表皮大致正常,真皮内一肿瘤团块,累及皮下脂肪,可见大量黏液样物质,其间细胞团块呈岛状漂浮.免疫病理示细胞角蛋白(CK)7、囊泡病液体蛋白(GCDFP)-15及前列腺特异性抗原(PSA)均阳性.诊断:原发性皮肤黏液癌.“,”A case of primary cutaneous mucinous carcinoma is reported.A 65-year-old man presented with a nodule on the left malar for more than one year.Dermatological examination revealed an elevated reddish nodule sized about 1.5 cm × 1 cm with clear boundaries,smooth surface and telangiectasia on the left malar.Histopathological examination revealed normal epidermis and a dermal tumor extended into the subcutaneous fatty tissue.A large number of mucus-like materials could be seen with islands of tumor cells floating in mucous materials.Immunohistochemical staining showed that tumor cells were positive for CK7,GCDFP-15 and PSA.The diagnosis of primary cutaneous mucinous carcinoma was made.